Fichier de travail (INPUT) : ./DUMP-TEXT/DUMP-1-32-utf8.txt
Encodage utilisé (INPUT) : UTF-8
Forme recherchée : schizophrénie|schizophrenia|統合失調症
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- Ligne n°22 : Schizophrenia Treatment & Management
- Ligne n°56 : Treatment of schizophrenia requires integration of medical,
Ligne n°57 : psychological, and psychosocial inputs. The bulk of care occurs in an ...
Ligne n°64 : ... It is important not to neglect the medical care of the person with- Ligne n°65 : schizophrenia. Obesity, diabetes, cardiovascular disease, and lung
Ligne n°66 : diseases are prevalent in schizophrenia, and the person with ...
Ligne n°65 : ... schizophrenia. Obesity, diabetes, cardiovascular disease, and lung- Ligne n°66 : diseases are prevalent in schizophrenia, and the person with
Ligne n°67 : schizophrenia often does not receive adequate medical care for such ...
Ligne n°66 : ... diseases are prevalent in schizophrenia, and the person with- Ligne n°67 : schizophrenia often does not receive adequate medical care for such
Ligne n°68 : conditions.^[78] ...
Ligne n°70 : ... Antipsychotic medications (also known as neuroleptic medications or- Ligne n°71 : major tranquilizers) diminish the positive symptoms of schizophrenia
Ligne n°72 : and prevent relapses. Approximately 80% of patients relapse within 1 ...
Ligne n°78 : ... The choice of which drug to use for treatment of a patient with- Ligne n°79 : schizophrenia depends on many issues, including effectiveness, cost,
Ligne n°80 : side-effect burden, method of delivery, availability, and tolerability. ...
Ligne n°87 : ... Although treatment is primarily provided on an outpatient basis,- Ligne n°88 : patients with schizophrenia may require hospitalization for
Ligne n°89 : exacerbation of symptoms caused by noncompliance with pharmacotherapy, ...- Ligne n°95 : Treatment of patients with schizophrenia, particularly during a
Ligne n°96 : psychotic episode, may raise the issue of informed consent. Consent is ...- Ligne n°103 : In the United States, patients with schizophrenia who are unable to
Ligne n°104 : work may be eligible for governmental programs, such as Medicare and ...
Ligne n°112 : ... The impact of the American Affordable Care Act (ACA) on the care of- Ligne n°113 : schizophrenia has yet to be determined. Some parts of the ACA, such as
Ligne n°114 : the removal of exclusion of preexisting conditions as a barrier to ...
Ligne n°187 : ... In CUtLASS (Cost Utility of the Latest Antipsychotic drugs in- Ligne n°188 : Schizophrenia Study), a study from the United Kingdom, more than 200
Ligne n°189 : patients who were about to change antipsychotic medication were ...- Ligne n°195 : First-episode schizophrenia
- Ligne n°197 : EUFEST (European First Episode Schizophrenia Trial) was a year-long
Ligne n°198 : open-label study conducted in nearly 500 patients in 13 European ...- Ligne n°215 : The Schizophrenia Patient Outcomes Research Team (PORT) of the
Ligne n°216 : University of Maryland recommended that any antipsychotic medication, ...
Ligne n°217 : ... with the exceptions of clozapine and olanzapine, can be used as- Ligne n°218 : first-line treatment for patients with schizophrenia who are
Ligne n°219 : experiencing their first episode of acute positive symptoms.^[87] ...- Ligne n°221 : According to a comprehensive review carried out by the Schizophrenia
Ligne n°222 : Patient Outcomes Research Team (PORT) of the University of Maryland, ...
Ligne n°228 : ... advised that neither drug should be considered as a first-line- Ligne n°229 : treatment for first-episode schizophrenia.^[87]
Ligne n°231 : ... Noting that both responsiveness to treatment and sensitivity to adverse- Ligne n°232 : effects are greater in patients with first-episode schizophrenia than
Ligne n°233 : in those who have had multiple episodes, PORT recommended starting ...
Ligne n°237 : ... ziprasidone have not been evaluated in first-episode- Ligne n°238 : schizophrenia.^[87]
Ligne n°250 : ... The National Institute of Mental Health (NIMH) has initiated a research- Ligne n°251 : project, Recovery After an Initial Schizophrenia Episode (RAISE), to
Ligne n°252 : determine whether coordinated and aggressive treatment in the earliest ...
Ligne n°252 : ... determine whether coordinated and aggressive treatment in the earliest- Ligne n°253 : stages of illness can prevent long-term disability from schizophrenia.
Ligne n°254 : The RAISE Early Treatment Program (ETP), an integrated program ...- Ligne n°261 : There is no clear antipsychotic drug of choice for schizophrenia.
Ligne n°262 : Clozapine is the most effective medication but is not recommended as ...- Ligne n°267 : Numerous guidelines or algorithms for the treatment of schizophrenia
Ligne n°268 : are available. Treatment guidelines are recommendations that require ...
Ligne n°273 : ... algorithms. In a study from Canada, Agid et al described the outcome of- Ligne n°274 : treatment among 244 patients with first-episode schizophrenia who were
Ligne n°275 : treated according to a 2003 algorithm.^[92] If no response to the first ...
Ligne n°300 : ... original medication. For example, quetiapine is sometimes prescribed at- Ligne n°301 : higher than approved doses for patients with schizophrenia or
Ligne n°302 : schizoaffective disorder. Honer et al found that dosages higher than ...- Ligne n°353 : Family members of people with schizophrenia, as well as clinicians
Ligne n°354 : providing care for them, should encourage them to take their ...
Ligne n°372 : ... reduction of risperidone or olanzapine dose by 50% improved cognitive- Ligne n°373 : function for stable patients with schizophrenia and did not lead to
Ligne n°374 : worsening of psychotic symptoms.^[100] ...
Ligne n°516 : ... antipsychotic therapy. In one randomized, placebo-controlled study- Ligne n°517 : conducted in 72 patients with first-episode schizophrenia who gained
Ligne n°518 : more than 7% of their predrug weight, metformin (1000 mg/day) was ...
Ligne n°544 : ... reached. For example, Ho et al performed structural brain imaging in- Ligne n°545 : more than 200 patients with schizophrenia over 7 years and found that
Ligne n°546 : whereas patients treated with higher doses of antipsychotic medications ...
Ligne n°559 : ... Regular measurement of blood medication levels in the blood would be- Ligne n°560 : helpful in schizophrenia, for the following reasons:
Ligne n°561 : * Patients may not always take their medications, and checking drug ...- Ligne n°596 : Many patients with schizophrenia are treated with other psychotropic
Ligne n°597 : medications in addition to antipsychotic agents. Polypharmacy in ...
Ligne n°597 : ... medications in addition to antipsychotic agents. Polypharmacy in- Ligne n°598 : schizophrenia is supported by little rigorous evidence but is widely
Ligne n°599 : practiced nonetheless. Medications often used include antidepressants, ...- Ligne n°612 : Psychosocial treatment is essential for people with schizophrenia and
Ligne n°613 : includes a number of approaches, such as social skills training, ...
Ligne n°619 : ... recovery model. According to this model, the goals of treatment for a- Ligne n°620 : person with schizophrenia are as follows:
Ligne n°621 : * To have few or stable symptoms ...- Ligne n°644 : Cognitive impairment, a core feature of schizophrenia, is less dramatic
Ligne n°645 : than other symptoms of the disease (eg, hallucinations and delusions) ...
Ligne n°684 : ... to be effective. In the study, 50 patients between the ages of 12 and- Ligne n°685 : 18 years with early onset schizophrenia were randomized to either
Ligne n°686 : cognitive remediation therapy plus usual treatment or usual treatment ...
Ligne n°695 : ... Cognitive therapy may be effective as a standalone treatment for- Ligne n°696 : schizophrenia.^[119, 120] For schizophrenic patients who cannot or will
Ligne n°697 : not take antipsychotic medication, cognitive therapy may be the most ...
Ligne n°698 : ... viable option. According to data from the first randomized trial of- Ligne n°699 : cognitive therapy as a standalone therapy for schizophrenia, structured
Ligne n°700 : treatment with a therapist significantly reduced the severity of ...
Ligne n°704 : ... The study involved 74 individuals aged 16 to 65 years with- Ligne n°705 : schizophrenia spectrum disorders who had decided not to take or had
Ligne n°706 : stopped taking antipsychotics for at least 6 months.^[119, 120] Half ...
Ligne n°716 : ... initiative from NIMH, known as Measurement and Treatment Research to- Ligne n°717 : Improve Cognition in Schizophrenia (MATRICS), is a collaboration
Ligne n°718 : between various programs to develop tools for measuring cognition in ...- Ligne n°724 : Most patients with schizophrenia would like to work; employment can
Ligne n°725 : improve income, self-esteem, and social status. However, few people ...- Ligne n°748 : Schizophrenia affects the person’s whole family, and the family’s
Ligne n°749 : responses can affect the trajectory of the person’s illness. Familial ...- Ligne n°761 : Most patients with schizophrenia smoke. This may be a result of
Ligne n°762 : previous conventional antipsychotic treatment, in that nicotine may ...
Ligne n°776 : ... Many psychotropic medications can cause weight gain and changes in- Ligne n°777 : glucose or lipid metabolism. Occasionally, a person with schizophrenia
Ligne n°778 : develops odd food preferences. Finally, many persons with schizophrenia ...
Ligne n°777 : ... glucose or lipid metabolism. Occasionally, a person with schizophrenia- Ligne n°778 : develops odd food preferences. Finally, many persons with schizophrenia
Ligne n°779 : have limited funds, do not cook for themselves, and live in areas where ...
Ligne n°784 : ... and because of the many beneficial effects of exercise, persons with- Ligne n°785 : schizophrenia should be encouraged to be as physically active as
Ligne n°786 : possible. ...- Ligne n°792 : Many have wondered whether patients with schizophrenia would have a
Ligne n°793 : better prognosis if treatment could be started as early as possible. A ...- Ligne n°805 : There are several studies of prodromal schizophrenia under way to
Ligne n°806 : inform early intervention strategies. In the absence of highly reliable ...
Ligne n°806 : ... inform early intervention strategies. In the absence of highly reliable- Ligne n°807 : methods of predicting schizophrenia, however, intervention during the
Ligne n°808 : prodromal stage could result in the unnecessary administration of ...
Ligne n°809 : ... antipsychotic medication to young people who are mistakenly identified- Ligne n°810 : as being at risk for schizophrenia.^[125]
Ligne n°813 : ... than pharmacotherapy. A German study of young people at risk for- Ligne n°814 : schizophrenia showed that the use of a psychological intervention
Ligne n°815 : involving cognitive-behavioral therapy, group skills training, ...- Ligne n°823 : An entirely different kind of treatment for schizophrenia, still in its
Ligne n°824 : early stages, is transcranial magnetic stimulation (TMS). TMS involves ...
Ligne n°830 : ... suggests that TMS, in some cases, may decrease auditory- Ligne n°831 : hallucinations^[127] and negative symptoms^[128] in schizophrenia.
Ligne n°832 : Previous ...
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Ligne n°896 : ... 9. Olabi B, Ellison-Wright I, McIntosh AM, et al. Are there- Ligne n°897 : progressive brain changes in schizophrenia? A meta-analysis of
Ligne n°898 : structural magnetic resonance imaging studies. Biol Psychiatry. Jul ...
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Ligne n°927 : Nature. Jul 24 2014;511(7510):421-7. [Medline]. ...
Ligne n°934 : ... association identifies a common variant in the reelin gene that- Ligne n°935 : increases the risk of schizophrenia only in women. PLoS Genet. Feb
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Ligne n°937 : ... 22. Wratten NS, Memoli H, Huang Y, Dulencin AM, Matteson PG, Cornacchia- Ligne n°938 : MA, et al. Identification of a schizophrenia-associated functional
Ligne n°939 : noncoding variant in NOS1AP. Am J Psychiatry. ...
Ligne n°941 : ... 23. O'Brien NL, Way MJ, Kandaswamy R, et al. The functional GRM3 Kozak- Ligne n°942 : sequence variant rs148754219 affects the risk of schizophrenia and
Ligne n°943 : alcohol dependence as well as bipolar disorder. Psychiatr Genet. ...
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Ligne n°951 : genetics and disease. Am J Psychiatry. Aug 2010;167(8):899-914. ...
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Ligne n°958 : speech and developmental delays and behavior problems. Genet Med. ...
Ligne n°961 : ... al. Confirmation and refinement of an 'at-risk' haplotype for- Ligne n°962 : schizophrenia suggests the EST cluster, Hs.97362, as a potential
Ligne n°963 : susceptibility gene at the Neuregulin-1 locus. Mol Psychiatry. Feb ...
Ligne n°965 : ... 29. Ekelund J, Hennah W, Hiekkalinna T, Parker A, Meyer J, Lönnqvist J,- Ligne n°966 : et al. Replication of 1q42 linkage in Finnish schizophrenia
Ligne n°967 : pedigrees. Mol Psychiatry. Nov 2004;9(11):1037-41. [Medline]. ...
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Ligne n°970 : and bipolar disorder. Mol Psychiatry. Sep 2009;14(9):865-73. ...
Ligne n°974 : ... physiology, cognition, neuronal repolarization and risk of- Ligne n°975 : schizophrenia. Nat Med. May 2009;15(5):509-18. [Medline]. [Full
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Ligne n°978 : ... al. Strong evidence for association between the dystrobrevin- Ligne n°979 : binding protein 1 gene (DTNBP1) and schizophrenia in 488
Ligne n°980 : parent-offspring trios from Bulgaria. Biol Psychiatry. May 15 ...
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Ligne n°991 : ... et al. Association and linkage disequilibrium between a functional- Ligne n°992 : polymorphism of the dopamine-2 receptor gene and schizophrenia in a
Ligne n°993 : genetically homogeneous Portuguese population. Mol Psychiatry. ...
Ligne n°996 : ... E, Weizman A, et al. A highly significant association between a- Ligne n°997 : COMT haplotype and schizophrenia. Am J Hum Genet. Dec
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Ligne n°1007 : ... Polymorphisms within 5' end of the Neuregulin 1 gene are- Ligne n°1008 : genetically associated with schizophrenia in the Chinese
Ligne n°1009 : population. Mol Psychiatry. Jan 2004;9(1):11-2. [Medline]. ...
Ligne n°1011 : ... et al. Fine mapping of ZNF804A and genome-wide significant evidence- Ligne n°1012 : for its involvement in schizophrenia and bipolar disorder. Mol
Ligne n°1013 : Psychiatry. Apr 2011;16(4):429-41. [Medline]. ...
Ligne n°1014 : ... 41. Xu B, Roos JL, Dexheimer P, et al. Exome sequencing supports a de- Ligne n°1015 : novo mutational paradigm for schizophrenia. Nat Genet. Aug 7
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Ligne n°1017 : ... 42. Girard SL, Gauthier J, Noreau A, et al. Increased exonic de novo- Ligne n°1018 : mutation rate in individuals with schizophrenia. Nat Genet. Jul 10
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Ligne n°1024 : ... 44. Fromer M, Pocklington AJ, Kavanagh DH, Williams HJ, Dwyer S,- Ligne n°1025 : Gormley P, et al. De novo mutations in schizophrenia implicate
Ligne n°1026 : synaptic networks. Nature. Jan 22 2014;[Medline]. ...
Ligne n°1027 : ... 45. Ripke S, O'Dushlaine C, Chambert K, et al. Genome-wide association- Ligne n°1028 : analysis identifies 13 new risk loci for schizophrenia. Nat Genet.
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Ligne n°1030 : ... 46. Lencz T, Guha S, Liu C, Rosenfeld J, Mukherjee S, Derosse P.- Ligne n°1031 : Genome-wide association study implicates NDST3 in schizophrenia and
Ligne n°1032 : bipolar disorder. Nat Commun. Nov 19 2013;4:2739. [Medline]. ...
Ligne n°1032 : ... bipolar disorder. Nat Commun. Nov 19 2013;4:2739. [Medline].- Ligne n°1033 : 47. Sullivan PF, Kendler KS, Neale MC. Schizophrenia as a complex
Ligne n°1034 : trait: evidence from a meta-analysis of twin studies. Arch Gen ...
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Ligne n°1037 : review of epidemiologic and translational studies. Am J Psychiatry. ...
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Ligne n°1047 : ... Evidence for an interaction between familial liability and prenatal- Ligne n°1048 : exposure to infection in the causation of schizophrenia. Am J
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Ligne n°1058 : ... 55. Haro JM, Novick D, Bertsch J, et al. Cross-national clinical and- Ligne n°1059 : functional remission rates: Worldwide Schizophrenia Outpatient
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Ligne n°1067 : study of linked English hospital episode statistics, 1999-2006. ...
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Ligne n°1081 : co-occurring substance use disorder. Am J Psychiatry. Mar ...
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Ligne n°1088 : meta-analysis of existing findings and new data in a first-episode ...
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Ligne n°1116 : substance abuse and prior offending in a sequential series of 435 ...
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Ligne n°1157 : Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia ...
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Ligne n°1350 : placebo-controlled study. J Clin Psychiatry. Nov ...
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Ligne n°1377 : follow-up in general hospital admissions. Presented at: The 22nd ...
Ligne n°1386 : ... Cortical activation patterns during verbal working memory maintenance.- Ligne n°1387 : Healthy controls (A), patients with schizophrenia (B), and
Ligne n°1388 : significantly different activation between groups (subtraction of ...
Ligne n°1395 : ... Park S. An event-related fMRI study of phonological verbal working- Ligne n°1396 : memory in schizophrenia. PLoS One. 2010; 5(8): e12068.
Ligne n°1397 : Cortical activation patterns during false memory trials. (A) False ...
Ligne n°1398 : ... memory, baseline in controls (CO). (B) False memory, baseline in- Ligne n°1399 : schizophrenia (SZ). (C) SZ – CO. All p-values are corrected with a
Ligne n°1400 : false discovery rate of q< 0.005. The time course plots show false ...
Ligne n°1403 : ... Matthews NL, and Park S. An event-related fMRI study of phonological- Ligne n°1404 : verbal working memory in schizophrenia. PLoS One. 2010; 5(8): e12068.
Ligne n°1405 : Magnetic resonance imaging showing differences in brain ventricle size ...
Ligne n°1405 : ... Magnetic resonance imaging showing differences in brain ventricle size- Ligne n°1406 : in twins. The twin on the right has schizophrenia, whereas the twin on
Ligne n°1407 : the left does not. Image courtesy of Dr. Daniel Weinberger, Clinical ...- Ligne n°1416 : Read more about Schizophrenia on Medscape
Ligne n°1417 : Related Reference Topics ...
Ligne n°1417 : ... Related Reference Topics- Ligne n°1418 : * Emergent Treatment of Schizophrenia
Ligne n°1419 : * Childhood-Onset Schizophrenia ...
Ligne n°1418 : ... * Emergent Treatment of Schizophrenia- Ligne n°1419 : * Childhood-Onset Schizophrenia
Ligne n°1420 : * Schizophreniform Disorder ...
Ligne n°1423 : ... * Feasibility, Acceptability, and Preliminary Efficacy of a- Ligne n°1424 : Smartphone Intervention for Schizophrenia
Ligne n°1425 : * Brain Structure Correlates of Urban Upbringing, an Environmental ...
Ligne n°1425 : ... * Brain Structure Correlates of Urban Upbringing, an Environmental- Ligne n°1426 : Risk Factor for Schizophrenia
Ligne n°1427 : * Positive Topline Phase 2 Results for Novel Schizophrenia Drug ...
Ligne n°1426 : ... Risk Factor for Schizophrenia- Ligne n°1427 : * Positive Topline Phase 2 Results for Novel Schizophrenia Drug